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Results for "

Camptothecin analog

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13670
    Lurtotecan

    GI147211; OSI-211

    		 Topoisomerase Cancer
    Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects .
    Lurtotecan
  • HY-156670
    Camptothecin analog-1

    		Others Others
    Camptothecin analog-1 (Comp 166) is a camptothecin analog .
    <em>Camptothecin</em> <em>analog</em>-1
  • HY-13622A
    Elomotecan

    BN 80927 free base

    		 Topoisomerase Cancer
    Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II. Elomotecan is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan reduces the proliferation of different tumor cells with higher potency than other anticancer agents of reference targeting topoisomerases I and II .
    Elomotecan
  • HY-13622
    Elomotecan hydrochloride

    BN 80927

    		 Topoisomerase Cancer
    Elomotecan hydrochloride (BN 80927) is a potent inhibitor of topoisomerases I and II. Elomotecan hydrochloride (BN 80927) is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan hydrochloride (BN 80927) reduces the proliferation of different tumor cells with higher potency than other anticancer agents of reference targeting topoisomerases I and II .
    Elomotecan hydrochloride
  • HY-156756
    7-Hydroxymethyl-10,11-MDCPT

    		ADC Cytotoxin Others
    7-Hydroxymethyl-10,11-MDCPT is a payload that can be used for ADC synthesis .
    7-Hydroxymethyl-10,11-MDCPT
  • HY-156756S
    7-Hydroxymethyl-10,11-MDCPT-d5

    		Isotope-Labeled Compounds ADC Cytotoxin
    7-Hydroxymethyl-10,11-MDCPT-d5 is deuterium labeled 7-Hydroxymethyl-10,11-MDCPT, which is a is a payload that can be used for ADC synthesis .
    7-Hydroxymethyl-10,11-MDCPT-d5
  • HY-128979
    Deruxtecan analog 2

    		Drug-Linker Conjugates for ADC Cancer
    Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC .
    Deruxtecan analog 2
  • HY-14833
    Atiratecan

    TP300

    		 Topoisomerase Cancer
    Atiratecan (TP300) is a proagent of camptothecin analog CH0793076 (HY-107096). Atiratecan does not inhibit acetylcholinesterase (AChE) activities. Atiratecan shows antitumor activity against both breast cancer resistance protein (BCRP)-positive and -negative xenografts in mouse xenograft models .
    Atiratecan
  • HY-107096
    CH-0793076

    TP3076

    		 Topoisomerase Cancer
    CH-0793076 (TP3076), a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein) .
    CH-0793076
  • HY-107096B
    CH-0793076 TFA

    TP3076 TFA

    		 Topoisomerase Cancer
    CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein) .
    CH-0793076 TFA
  • HY-W021377C
    Exatecan Intermediate 4 dihydrochloride

    		ADC Cytotoxin Topoisomerase Cancer
    Exatecan Intermediate 4 dihydrochloride is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 4 dihydrochloride
  • HY-W021377
    Exatecan Intermediate 2

    		ADC Cytotoxin Topoisomerase Cancer
    Exatecan Intermediate 2 (compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 2
  • HY-42487
    Exatecan Intermediate 1

    		ADC Cytotoxin Topoisomerase Cancer
    Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 1
  • HY-W021377A
    Exatecan Intermediate 2 hydrochloride

    		ADC Cytotoxin Topoisomerase Cancer
    Exatecan Intermediate 2 hydrochloride (compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 2 hydrochloride
  • HY-W021377B
    Exatecan Intermediate 4

    		ADC Cytotoxin Topoisomerase Cancer
    Exatecan Intermediate 4 (compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 4

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